Description

6-Bromo-8-Iodoquinoline is a high-purity halogenated quinoline derivative, a crucial building block in advanced organic synthesis. Its unique bifunctional halogen pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition or acting as receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with enhanced activity profiles.
• Ligand Synthesis: Serves as a versatile scaffold for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to the quinoline core.
• Cross-Coupling Reactions: The bromo and iodo substituents are orthogonal handles for sequential Suzuki, Stille, or Sonogashira cross-coupling reactions.
• Chemical Biology Probes: Useful for tagging and modifying biomolecules in probe development and bioconjugation strategies.

Basic Information

Product Name	6-Bromo-8-Iodoquinoline
CAS No.	1078160-90-3
Molecular Formula	C9H5BrIN
Molecular Weight	333.95 g/mol
Synonyms	8-Iodo-6-bromoquinoline; Quinoline, 6-bromo-8-iodo-; 6-Bromo-8-iodoquinoline; 1078160-90-3; 6-Br-8-I-quinoline
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-8-Iodoquinoline is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.