Description

8-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-2-Carboxylic Acid Methyl Ester is a high-purity fluorinated quinoline derivative, a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. Pharmaceutical R&D laboratories and fine chemical manufacturers need this ester for its precise molecular architecture, enabling the synthesis of complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of next-generation fluoroquinolone antibiotics and other bioactive molecules.
• Organic Synthesis Research: Key starting material or intermediate in academic and industrial research for developing novel heterocyclic compounds.
• Agrochemical Development: Used in the research and synthesis of new agrochemicals, leveraging the fluorinated quinoline scaffold for enhanced properties.
• Material Science Precursor: Potential precursor for the development of specialty chemicals and advanced organic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	8-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-2-Carboxylic Acid Methyl Ester
CAS No.	1078130-52-5
Molecular Formula	C12H8FNO3
Molecular Weight	233.20 g/mol
Synonyms	Methyl 8-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate; 8-Fluoro-1,4-dihydro-4-oxoquinoline-2-carboxylic acid methyl ester; 1,4-Dihydro-8-fluoro-4-oxo-2-quinolinecarboxylic acid methyl ester; 2-Quinolinecarboxylic acid, 1,4-dihydro-8-fluoro-4-oxo-, methyl ester; 8-Fluoro-4-oxo-1H-quinoline-2-carboxylic acid methyl ester; 8-Fluoroquinolone-2-carboxylic acid methyl ester; CAS 1078130-52-5
EINECS	Contact for details

Quality Control

Our 8-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-2-Carboxylic Acid Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.