Description

2-Amino-1-(4'-Methoxy-3'-Sulfonamidophenyl)-2-Propanone, Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex aromatic ketone structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in specialized therapeutic areas. It is primarily needed by research institutions, custom synthesis organizations, and pharmaceutical manufacturers engaged in the development of new chemical entities and complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of target drug molecules, especially those with sulfonamide and methoxy phenyl moieties.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new pharmacologically active compounds.
• Custom Synthesis: Serves as a specialized starting material or intermediate for contract research and manufacturing organizations (CROs/CMOs).
• API Synthesis: Integral to the production pathway of complex APIs targeting specific receptors or enzymes.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	2-Amino-1-(4'-Methoxy-3'-Sulfonamidophenyl)-2-Propanone, Hydrochloride
CAS No.	1076198-82-7
Molecular Formula	C11H15N2O4S • HCl
Molecular Weight	308.77 g/mol (Free base: 271.31 g/mol)
Synonyms	1-(4-Methoxy-3-sulfamoylphenyl)-2-aminopropan-1-one hydrochloride; 2-Amino-1-(4-methoxy-3-sulfonamidophenyl)propan-1-one HCl; 2-Amino-1-(3-sulfamoyl-4-methoxyphenyl)propan-1-one hydrochloride; 2-Amino-1-(4-methoxy-3-sulfamoylphenyl)-2-propanone hydrochloride; 3'-Sulfamoyl-4'-methoxy-2-aminopropiophenone hydrochloride; α-Aminoisopropyl 4-methoxy-3-sulfamoylphenyl ketone hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Every batch is characterized and controlled using modern analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.