Description

5-Boc-1-Phenyl-1,4,6,7-Tetrahydropyrazolo[4,3-C]Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degradation therapeutics.
• Kinase Inhibitor Synthesis: Employed in the construction of heterocyclic cores for potential kinase inhibitors, relevant in oncology and inflammatory disease research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of candidate drugs under cGMP conditions.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-Boc-1-Phenyl-1,4,6,7-Tetrahydropyrazolo[4,3-C]Pyridine
CAS No.	1075729-08-6
Molecular Formula	C21H25N3O2
Molecular Weight	351.45 g/mol
Synonyms	1,4,6,7-Tetrahydro-5-[[(1,1-dimethylethoxy)carbonyl]-1-phenylpyrazolo[4,3-c]pyridine; tert-Butyl 1-phenyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine-5-carboxylate; 5-(tert-Butoxycarbonyl)-1-phenyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine; 5-Boc-1-phenyl-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridine; 1-Phenyl-5-Boc-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine; Boc-protected phenyl-tetrahydropyrazolopyridine
EINECS	Contact for details

Quality Control

Our 5-Boc-1-Phenyl-1,4,6,7-Tetrahydropyrazolo[4,3-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we can support development projects requiring material produced under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.