Description

S-3-(Boc-Aminomethyl)-Pyrrolidine-Hcl is a high-purity, chiral pyrrolidine derivative protected with a tert-butoxycarbonyl (Boc) group. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs). It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries requiring enantiomerically pure intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Peptidomimetics & PROTACs: Used in the design and synthesis of peptidomimetic compounds and Proteolysis Targeting Chimeras (PROTACs) due to its rigid pyrrolidine scaffold and protected amine functionality.
• Asymmetric Catalysis Ligand Precursor: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Agrochemical Research: Employed in the development of enantiomerically pure agrochemicals, such as herbicides and fungicides, where specific stereochemistry is crucial for activity.
• Academic & R&D: A valuable reagent for medicinal chemistry research and process development in university and industrial R&D laboratories.
• Custom Synthesis: Used as a starting material for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	S-3-(Boc-Aminomethyl)-Pyrrolidine-Hcl
CAS No.	1075260-66-0
Molecular Formula	C11H22N2O2 • HCl
Molecular Weight	250.77 g/mol (Free base: 214.30 g/mol)
Synonyms	(S)-3-((tert-Butoxycarbonylamino)methyl)pyrrolidine hydrochloride; (S)-1-Boc-3-(aminomethyl)pyrrolidine HCl; (S)-N-Boc-3-(aminomethyl)pyrrolidine hydrochloride; (S)-3-(Boc-aminomethyl)pyrrolidine HCl; tert-Butyl ((S)-pyrrolidin-3-ylmethyl)carbamate hydrochloride; (S)-3-(BocNHCH2)-pyrrolidine hydrochloride; (S)-3-(Boc-Aminomethyl)pyrrolidine Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our S-3-(Boc-Aminomethyl)-Pyrrolidine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.