Description

2-(Difluoromethyl)Quinoline is a high-purity, specialized fluorinated heterocyclic compound serving as a critical building block in advanced chemical synthesis. Its unique difluoromethyl-quinoline structure makes it a valuable intermediate for developing novel pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability. This compound is essential for research and production in medicinal chemistry, particularly for creating new active ingredients targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the difluoromethyl group can improve efficacy and environmental profile.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Versatile building block for introducing the quinoline scaffold and difluoromethyl moiety into more complex molecular architectures in organic chemistry.
• Life Science Research: Employed as a probe or tool compound in biochemical and pharmacological studies to investigate enzyme function and cellular pathways.

Basic Information

Product Name	2-(Difluoromethyl)Quinoline
CAS No.	1075184-01-8
Molecular Formula	C10H7F2N
Molecular Weight	179.17 g/mol
Synonyms	Quinoline, 2-(difluoromethyl)-; 2-(Difluoromethyl)quinoline; 2-Quinolinecarboxaldehyde, difluoro-; 1075184-01-8; Difluoromethylquinoline; 2-Difluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.