Description

Methyl 4-Hydroxy-7-(Trifluoromethyl)Quinoline-2-Carboxylate is a high-value, multifunctional heterocyclic building block distinguished by its quinoline core and strategically positioned trifluoromethyl and ester functional groups. This compound is critical for research and development in advanced organic synthesis, enabling the creation of novel molecules with tailored properties. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for its role as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in developing molecules with potential anti-infective, anti-inflammatory, or kinase inhibitory activity.
• Agrochemical Research: Serves as a building block for creating new herbicides, fungicides, or insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Used in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport materials, due to its rigid, conjugated quinoline structure.
• Chemical Synthesis: Functions as a versatile synthon for further derivatization, including hydrolysis to the corresponding acid, amidation, or nucleophilic substitution reactions.
• Fluorine Chemistry Research: An important compound for studying the influence of the trifluoromethyl group on the physicochemical and biological properties of quinoline derivatives.

Basic Information

Product Name	Methyl 4-Hydroxy-7-(Trifluoromethyl)Quinoline-2-Carboxylate
CAS No.	1072944-69-4
Molecular Formula	C₁₂H₈F₃NO₃
Molecular Weight	271.19 g/mol
Synonyms	Methyl 4-hydroxy-7-(trifluoromethyl)-2-quinolinecarboxylate; 7-(Trifluoromethyl)-4-hydroxyquinoline-2-carboxylic acid methyl ester; 4-Hydroxy-7-trifluoromethylquinoline-2-carboxylic acid methyl ester; 2-Quinolinecarboxylic acid, 4-hydroxy-7-(trifluoromethyl)-, methyl ester; Methyl 4-hydroxy-7-trifluoromethylquinoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Hydroxy-7-(Trifluoromethyl)Quinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.