Description

Methyl 8-Bromo-4-Chloroquinoline-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting complex therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of quinoline-based compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with quinoline scaffolds for potential antimicrobial, anticancer, or anti-inflammatory applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of halogenated quinoline derivatives.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of reactive bromo and chloro substituents, enabling further functionalization.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new reaction pathways in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Methyl 8-Bromo-4-Chloroquinoline-2-Carboxylate
CAS No.	1072944-68-3
Molecular Formula	C11H7BrClNO2
Molecular Weight	300.54 g/mol
Synonyms	Methyl 8-bromo-4-chloro-2-quinolinecarboxylate; 8-Bromo-4-chloroquinoline-2-carboxylic acid methyl ester; 2-Quinolinecarboxylic acid, 8-bromo-4-chloro-, methyl ester; 8-Bromo-4-chloro-quinoline-2-carboxylic acid methyl ester; Methyl 8-bromo-4-chloroquinoline-2-carboxylate; 1072944-68-3
EINECS	Contact for details

Quality Control

Our Methyl 8-Bromo-4-Chloroquinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.