Description

4-Bromo-7-Chloro-8-Methyl-2-(Trifluoromethyl)Quinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex halogenated and trifluoromethylated quinoline structure makes it a critical intermediate for developing novel compounds with tailored properties. This product is primarily targeted at pharmaceutical R&D and agrochemical discovery programs seeking to incorporate unique fluorinated motifs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting infectious diseases, oncology, and central nervous system disorders.
• Agrochemical Research: Serves as a core scaffold for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research and development of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Ligand & Catalyst Development: Employed to create novel nitrogen-containing ligands for transition metal catalysis in fine chemical synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal and agrochemical chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client projects.

Basic Information

Item	Details
Product Name	4-Bromo-7-Chloro-8-Methyl-2-(Trifluoromethyl)Quinoline
CAS No.	1072944-67-2
Molecular Formula	C₁₁H₆BrClF₃N
Molecular Weight	324.52 g/mol
Synonyms	4-Bromo-7-chloro-8-methyl-2-(trifluoromethyl)quinoline; 8-Methyl-4-bromo-7-chloro-2-trifluoromethylquinoline; Quinoline, 4-bromo-7-chloro-8-methyl-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-4-bromo-7-chloro-8-methylquinoline; 4-Bromo-7-chloro-8-methyl-2-trifluoromethylquinoline; 1072944-67-2; 4-Br-7-Cl-8-Me-2-CF3-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-7-Chloro-8-Methyl-2-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected for GMP-grade intermediates used in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged procedures to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.