Description

3-Bromo-6-Fluoro-2-(Trifluoromethyl)Quinolin-4-Ol CAS NO 1072944-66-1 is a high-value, multi-functionalized quinoline derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to incorporate complex halogenated and fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or requiring fluorinated bioisosteres.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the quinoline scaffold and halogen atoms contribute to biological activity.
• Material Science Building Block: Employed in the creation of advanced organic electronic materials, such as OLEDs or semiconductors, due to its electron-deficient and rigid structure.
• Chemical Synthesis: Serves as a versatile substrate for further functionalization via cross-coupling reactions, nucleophilic substitutions, or metal-catalyzed transformations.
• Ligand and Catalyst Development: Utilized in the design of novel chelating ligands or organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of multiple fluorine atoms on chemical reactivity and physical properties.

Basic Information

Product Name	3-Bromo-6-Fluoro-2-(Trifluoromethyl)Quinolin-4-Ol
CAS No.	1072944-66-1
Molecular Formula	C₁₁H₄BrF₄NO
Molecular Weight	322.06 g/mol
Synonyms	4-Hydroxy-3-bromo-6-fluoro-2-(trifluoromethyl)quinoline; 3-Bromo-6-fluoro-2-(trifluoromethyl)-4-quinolinol; 3-Bromo-6-fluoro-2-(trifluoromethyl)quinolin-4-ol; 1072944-66-1; 4-Quinolinol, 3-bromo-6-fluoro-2-(trifluoromethyl)-; 3-Bromo-6-fluoro-2-trifluoromethylquinolin-4-ol
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Fluoro-2-(Trifluoromethyl)Quinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support custom synthesis and can tailor purity grades to meet specific project requirements, from research (95%+) to advanced pharmaceutical intermediate (98%+) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (Advanced Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.