Description

1-(2-Nitro-5-Trifluoromethylphenyl)Piperidin-4-Ol is a high-value, multi-functional chemical intermediate characterized by its unique aromatic nitro and trifluoromethyl substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, due to the piperidin-ol scaffold.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced polymers and functional materials that require nitro-aromatic or fluorinated components.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways in research settings.

Basic Information

Product Name	1-(2-Nitro-5-Trifluoromethylphenyl)Piperidin-4-Ol
CAS No.	1072944-51-4
Molecular Formula	C12H13F3N2O3
Molecular Weight	290.24 g/mol
Synonyms	4-Piperidinol, 1-[2-nitro-5-(trifluoromethyl)phenyl]-; 1-(2-Nitro-5-(trifluoromethyl)phenyl)-4-piperidinol; 1-(2-Nitro-5-trifluoromethylphenyl)-4-hydroxypiperidine; 4-Hydroxy-1-(2-nitro-5-trifluoromethylphenyl)piperidine; 1072944-51-4; 1-(2-Nitro-5-Trifluoromethylphenyl)Piperidin-4-Ol
EINECS	Contact for details

Quality Control

Our production of 1-(2-Nitro-5-Trifluoromethylphenyl)Piperidin-4-Ol adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.