Description

4-(2-Nitrophenoxy)Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1072944-49-0. This compound is a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the production of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Serves as a building block for creating complex, high-value specialty chemicals and custom synthesis projects.
• Academic & Industrial R&D: Employed in research laboratories for developing new synthetic methodologies and exploring novel chemical entities.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and pesticides.

Basic Information

Product Name	4-(2-Nitrophenoxy)Piperidine Hydrochloride
CAS No.	1072944-49-0
Molecular Formula	C11H14N2O3·HCl
Molecular Weight	270.70 g/mol
Synonyms	4-(2-Nitrophenoxy)piperidine hydrochloride; 4-(2-Nitrophenoxy)piperidine HCl; Piperidine, 4-(2-nitrophenoxy)-, hydrochloride (1:1); 4-(2-Nitro-phenoxy)-piperidine hydrochloride; 4-(o-Nitrophenoxy)piperidine hydrochloride; 1-(2-Nitrophenoxy)-4-piperidine hydrochloride; 4-(2-Nitrophenoxy)piperidinium chloride
EINECS	Contact for details

Quality Control

Our 4-(2-Nitrophenoxy)Piperidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.