Description

6-Bromo-2-Methylpyridine-3-Boronic Acid is a versatile and high-value boronic acid derivative, a key building block in modern synthetic chemistry. Its primary value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used to create novel pyridine-based herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & OLED Development: Serves as a building block for constructing advanced organic ligands and functional molecules used in organic light-emitting diodes (OLEDs) and electronic materials.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura cross-coupling to form biaryl and heterobiaryl structures, a cornerstone of modern C-C bond formation.
• Ligand & Catalyst Design: Utilized in the development of novel bidentate ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable tool for medicinal and process chemists in lead optimization, structure-activity relationship (SAR) studies, and route scouting.

Basic Information

Product Name	6-Bromo-2-Methylpyridine-3-Boronic Acid
CAS No.	1072944-22-9
Molecular Formula	C7H9BBrNO2
Molecular Weight	229.87 g/mol
Synonyms	(6-Bromo-2-methylpyridin-3-yl)boronic acid; 2-Methyl-6-bromopyridine-3-boronic acid; 3-Borono-6-bromo-2-methylpyridine; 6-Bromo-2-methyl-3-pyridineboronic acid; 6-Bromo-2-picoline-3-boronic acid; 2-Methyl-6-bromo-3-pyridinylboronic acid; Boronic acid, B-(6-bromo-2-methyl-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Methylpyridine-3-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening a new container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.