Description

Fmoc-3-Amino-4-Methylbenzoic Acid is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled and sequential assembly of complex peptides and peptidomimetics. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in drug discovery, proteomics research, and the development of therapeutic peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the Fmoc-strategy, facilitating the incorporation of a modified tyrosine-like residue into peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of novel peptide-based drug candidates, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Combinatorial Chemistry Libraries: Serves as a versatile scaffold for generating diverse arrays of compounds for high-throughput screening against biological targets.
• Bioconjugation and Probe Development: The carboxylic acid and protected amine functionalities allow for site-specific labeling and conjugation to other molecules, proteins, or surfaces.
• Academic Research: Employed in biochemistry and chemical biology laboratories for studying protein-protein interactions, signal transduction, and developing research tools.

Basic Information

Product Name	Fmoc-3-Amino-4-Methylbenzoic Acid
CAS No.	1072901-59-7
Molecular Formula	C23H19NO4
Molecular Weight	373.40 g/mol
Synonyms	Fmoc-3-Amino-4-methylbenzoic acid; 4-Methyl-3-[(9H-fluoren-9-ylmethoxy)carbonylamino]benzoic acid; 3-[(Fmoc-amino]-4-methylbenzoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-4-methylbenzoic acid; Fmoc-3-Amino-p-toluic Acid; Fmoc-MeTyr(3-NH2)-OH; Fmoc-3-Amino-4-MBA
EINECS	Contact for details

Quality Control

Our Fmoc-3-Amino-4-Methylbenzoic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant industry standards for fine chemicals used in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.