Description

Ethyl [(7-Chloroquinolin-4-Yl)Thio]Acetate is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting infectious diseases or possessing antimalarial activity.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the bioactive quinoline core.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular tools to study biological pathways and protein functions.
• Material Science Research: Employed in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting exploratory chemistry and method development.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes from laboratory scale to potential pilot-scale production.

Basic Information

Product Name	Ethyl [(7-Chloroquinolin-4-Yl)Thio]Acetate
CAS No.	1071597-98-2
Molecular Formula	C₁₃H₁₂ClNO₂S
Molecular Weight	281.76 g/mol
Synonyms	Ethyl (7-chloro-4-quinolylthio)acetate; Acetic acid, 2-[(7-chloro-4-quinolinyl)thio]-, ethyl ester; 7-Chloro-4-mercaptoquinoline ethyl thioacetate; Ethyl 2-((7-chloroquinolin-4-yl)thio)acetate; 4-Quinolinethiol, 7-chloro-, acetate (ester); Ethyl [(7-chloro-4-quinolinyl)thio]acetate
EINECS	Contact for details

Quality Control

Our Ethyl [(7-Chloroquinolin-4-Yl)Thio]Acetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.