Description

8-Chloro-1,5-naphthyridin-3-ol is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique heterocyclic structure, which provides a versatile scaffold for constructing complex molecules with targeted biological or material properties. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, catalyst development, and the creation of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probe: Utilized as a core structure for designing molecular probes to study biological processes and protein functions.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	8-Chloro-1,5-naphthyridin-3-ol
CAS No.	1071541-08-6
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	8-Chloro-1,5-naphthyridin-3-ol; 3-Hydroxy-8-chloro-1,5-naphthyridine; 8-Chloro-3-hydroxy-1,5-naphthyridine; 1,5-Naphthyridin-3-ol, 8-chloro-; 1071541-08-6; 8-Chloro-1,5-naphthyridin-3-ol; 8-Chloro-3-hydroxy-[1,5]naphthyridine
EINECS	Contact for details

Quality Control

Our 8-Chloro-1,5-naphthyridin-3-ol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This compound may be light-sensitive and/or moisture-sensitive; prolonged exposure to light or humidity should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.