Description

5-Chlorothiophen-2-Amine Hydrochloride is a high-purity organic building block essential for advanced chemical synthesis. This compound matters as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals, where its specific halogenated thiophene structure enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorothiophene moiety.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of conductive polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and affinity tags to study biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	5-Chlorothiophen-2-Amine Hydrochloride
CAS No.	1070886-43-9
Molecular Formula	C4H5Cl2NS
Molecular Weight	178.06 g/mol
Synonyms	2-Amino-5-chlorothiophene Hydrochloride; 5-Chloro-2-thiophenamine Hydrochloride; 5-Chloro-2-aminothiophene Hydrochloride; 2-Thiophenamine, 5-chloro-, hydrochloride; 5-Chlorothiophen-2-ylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Chlorothiophen-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.