Description

4-Bromo-5,8-Dichloro-2-Methylquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique halogen substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex heterocyclic architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, antimicrobial agents, and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and pesticides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a precursor for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and functional dyes.
• Chemical Synthesis: Acts as a versatile substrate in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the presence of bromo and chloro leaving groups.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in university and corporate research laboratories.

Basic Information

Item	Detail
Product Name	4-Bromo-5,8-Dichloro-2-Methylquinoline
CAS No.	1070879-63-8
Molecular Formula	C10H6BrCl2N
Molecular Weight	291.97 g/mol
Synonyms	2-Methyl-4-bromo-5,8-dichloroquinoline; 5,8-Dichloro-4-bromo-2-methylquinoline; 4-Bromo-5,8-dichloro-2-methyl-quinoline; Quinoline, 4-bromo-5,8-dichloro-2-methyl-; 1070879-63-8
EINECS	Contact for details

Quality Control

Our 4-Bromo-5,8-Dichloro-2-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area Percent)
Purity (HPLC)	≥95.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.