Description

4-Bromo-2-Methyl-8-Trifluoromethylquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring bromine and trifluoromethyl substituents on a quinoline core, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new generation pesticides, herbicides, and fungicides with improved efficacy and environmental profiles.
• Material Science: Used in the research and development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient quinoline structure.
• Chemical Biology Probe: Employed as a building block for creating fluorescent tags, enzyme inhibitors, and other molecular probes for biological research and diagnostic applications.
• Catalyst Ligand Synthesis: Acts as a starting material for synthesizing sophisticated nitrogen-containing ligands used in transition metal catalysis for asymmetric synthesis.

Basic Information

Product Name	4-Bromo-2-Methyl-8-Trifluoromethylquinoline
CAS No.	1070879-58-1
Molecular Formula	C11H7BrF3N
Molecular Weight	290.08 g/mol
Synonyms	8-Trifluoromethyl-4-bromo-2-methylquinoline; 2-Methyl-4-bromo-8-(trifluoromethyl)quinoline; 4-Bromo-2-methyl-8-(trifluoromethyl)quinoline; Quinoline, 4-bromo-2-methyl-8-(trifluoromethyl)-; 1070879-58-1
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methyl-8-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.