Description

4-Bromo-2-Methyl-7-Trifluoromethylquinoline is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for advanced organic synthesis, offering versatile reactivity for cross-coupling reactions and serving as a key precursor in the development of complex molecules. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the quinoline scaffold and halogen/fluoro groups can contribute to bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic electronic materials, such as OLEDs or conductive polymers, due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, enabling rapid diversification of molecular structures.
• Ligand Synthesis: Utilized for constructing complex nitrogen-containing ligands for catalysis and coordination chemistry.
• Fluorinated Compound Library: A valuable starting material for generating libraries of fluorinated compounds in discovery chemistry, leveraging the properties of the CF3 group.

Basic Information

Product Name	4-Bromo-2-Methyl-7-Trifluoromethylquinoline
CAS No.	1070879-57-0
Molecular Formula	C11H7BrF3N
Molecular Weight	290.08 g/mol
Synonyms	4-Bromo-2-methyl-7-(trifluoromethyl)quinoline; 7-Trifluoromethyl-4-bromo-2-methylquinoline; 2-Methyl-4-bromo-7-trifluoromethylquinoline; Quinoline, 4-bromo-2-methyl-7-(trifluoromethyl)-; 4-Bromo-2-methyl-7-trifluoromethyl-quinoline; 4-Br-2-Me-7-CF3-Quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methyl-7-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.