Description

6-Amino-1,4,8-Trioxaspiro[4.5]Decane is a specialized spirocyclic amino acetal building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, which combines a protected amine functionality with a rigid, oxygen-rich spirocyclic framework, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst design, and the synthesis of novel heterocycles.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring rigid, three-dimensional scaffolds.
• Ligand and Catalyst Synthesis: Utilized in the development of novel chelating ligands and organocatalysts due to its nitrogen and oxygen donor atoms within a constrained geometry.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating polymers with specific thermal and mechanical properties.
• Agrochemical Research: Employed in the design and synthesis of new herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the development of advanced materials, such as metal-organic frameworks (MOFs) and functional coatings.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	6-Amino-1,4,8-Trioxaspiro[4.5]Decane
CAS No.	1068523-26-1
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	6-Amino-1,4,8-trioxaspiro[4.5]decane; 1,4,8-Trioxaspiro[4.5]decan-6-amine; 6-Amino-1,4,8-trioxaspiro(4.5)decane; Spirocyclic amino acetal; Amino spiroketal
EINECS	Contact for details

Quality Control

Our 6-Amino-1,4,8-Trioxaspiro[4.5]Decane is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.