Description

2-(2-Bromo-Pyridin-3-Yloxy)-4-Chloro-Pyrimidine is a high-purity (98+%) heterocyclic building block with the molecular formula C9H5BrClN3O and a molecular weight of 286.52. This compound is a critical intermediate in modern pharmaceutical and agrochemical research, valued for its unique halogenated pyridine-pyrimidine structure that enables precise molecular modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex active molecules.

Application

This versatile chemical intermediate is designed for advanced synthetic applications. Key uses include:

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic core.
• Chemical Biology & Proteomics: Serves as a valuable scaffold or linker in the design of molecular probes and tool compounds for target identification and validation.
• Material Science: Potential precursor for the synthesis of specialized ligands in catalysis or functional organic materials.
• Custom Synthesis & Contract Manufacturing: An essential raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-(2-Bromo-Pyridin-3-Yloxy)-4-Chloro-Pyrimidine
CAS No.	1065484-67-4
Molecular Formula	C9H5BrClN3O
Molecular Weight	286.52 g/mol
Synonyms	4-Chloro-2-[(2-bromopyridin-3-yl)oxy]pyrimidine; 2-[(2-Bromo-3-pyridinyl)oxy]-4-chloropyrimidine; 4-Chloro-2-(2-bromopyridin-3-yloxy)pyrimidine; 2-(2-Bromopyridin-3-yloxy)-4-chloropyrimidine; Pyrimidine, 4-chloro-2-[(2-bromo-3-pyridinyl)oxy]-; 1065484-67-4; 2-(2-Bromo-3-pyridyloxy)-4-chloropyrimidine
EINECS	Contact for details

Quality Control

Our 2-(2-Bromo-Pyridin-3-Yloxy)-4-Chloro-Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the specified purity of 98+% and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). The product is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC / NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.