Description

(R)-1-(2-Chloro-8-Fluoroquinolin-3-Yl)Ethanol is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because its defined stereochemistry is crucial for the development of active pharmaceutical ingredients (APIs) with specific biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the production of novel therapeutics.

Application

• Key chiral building block for the synthesis of novel fluoroquinolone antibiotic candidates.
• Critical intermediate in the research and development of pharmaceutical compounds targeting bacterial infections.
• Used in asymmetric synthesis to construct complex molecules with defined stereocenters.
• Precursor for the development of active pharmaceutical ingredients (APIs) in preclinical and clinical studies.
• Valuable reagent in medicinal chemistry research for structure-activity relationship (SAR) studies.
• Starting material for custom synthesis services in the fine chemical and contract manufacturing sectors.

Basic Information

Product Name	(R)-1-(2-Chloro-8-Fluoroquinolin-3-Yl)Ethanol
CAS No.	1065481-27-7
Molecular Formula	C₁₁H₉ClFNO
Molecular Weight	225.65 g/mol
Synonyms	(3R)-1-(2-Chloro-8-fluoro-3-quinolyl)ethanol; (R)-1-(2-Chloro-8-fluoroquinolin-3-yl)ethan-1-ol; (R)-2-Chloro-8-fluoro-3-(1-hydroxyethyl)quinoline; (R)-1-(2-Chloro-8-fluoro-3-quinolinyl)ethanol; (R)-1-(2-Chloro-8-fluoroquinolin-3-yl)ethanol; (R)-1-(2-Chloro-8-fluoro-3-quinolyl)ethan-1-ol; (R)-2-Chloro-8-fluoro-3-(1-hydroxyethyl)quinoline
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Chloro-8-Fluoroquinolin-3-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.