Description

8-Bromo-5-Fluoroquinolin-4-Ol is a high-purity fluorinated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which is essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antibacterial and antiviral agents targeting DNA gyrase and topoisomerase enzymes.
• Agrochemical Research: Used in developing next-generation fungicides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a molecular probe or labeling agent due to its reactive bromo and hydroxyl functional groups.
• Academic & Contract Research: Essential for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	8-Bromo-5-Fluoroquinolin-4-Ol
CAS No.	1065092-35-4
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	8-Bromo-5-fluoro-4-hydroxyquinoline; 4-Hydroxy-8-bromo-5-fluoroquinoline; 5-Fluoro-8-bromoquinolin-4-ol; 8-Bromo-5-fluoro-4-quinolinol; 1065092-35-4; 8-Br-5-F-quinolin-4-ol
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoroquinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, prolonged exposure to light and air should be avoided. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.