Description

4-Amino-5,7-Difluoroquinoline is a high-value, fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and fluorine substituents, makes it an essential precursor for developing novel compounds with tailored properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology and antimicrobial research, leveraging the quinoline scaffold's biological activity.
• Agrochemical Research: Used in the synthesis of new-generation pesticides and herbicides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Precursor: Employed in the creation of specialized organic ligands for catalysis and in the development of advanced functional materials.
• Chemical Synthesis Building Block: Facilitates the construction of complex heterocyclic compounds for various research applications in fine chemicals.
• Fluorine Chemistry Studies: Serves as a model compound in academic and industrial research focused on the synthesis and reactivity of fluorinated heterocycles.

Basic Information

Product Name	4-Amino-5,7-Difluoroquinoline
CAS No.	1065092-27-4
Molecular Formula	C9H6F2N2
Molecular Weight	180.16 g/mol
Synonyms	5,7-Difluoroquinolin-4-amine; 4-Amino-5,7-difluoroquinoline; Quinoline, 4-amino-5,7-difluoro-; 5,7-Difluoro-4-quinolinamine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-5,7-Difluoroquinoline is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.