Description

4-Amino-3-Bromo-6-Trifluoromethylquinoline is a high-value, multi-functional heterocyclic building block. This compound is strategically important for the development of novel active pharmaceutical ingredients (APIs) and advanced materials due to its unique trifluoromethyl and halogenated quinoline scaffold. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of potential drug candidates, particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a fluorescent tag or labeling reagent due to the quinoline core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring complex fluorinated heterocycles.

Basic Information

Product Name	4-Amino-3-Bromo-6-Trifluoromethylquinoline
CAS No.	1065088-40-5
Molecular Formula	C10H6BrF3N2
Molecular Weight	291.07 g/mol
Synonyms	3-Bromo-4-amino-6-(trifluoromethyl)quinoline; 6-Trifluoromethyl-3-bromoquinolin-4-amine; 4-Amino-3-bromo-6-(trifluoromethyl)quinoline; Quinoline, 4-amino-3-bromo-6-(trifluoromethyl)-; 1065088-40-5
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-6-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.