Description

4-Amino-3-Bromo-6-Chloroquinoline is a high-purity, multi-functional halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring distinct amino, bromo, and chloro substituents, makes it an invaluable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical developers for the synthesis of novel active pharmaceutical ingredients (APIs) and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimalarial, anticancer, and antimicrobial applications.
• Agrochemical Research: Used in developing advanced fungicides and herbicides, leveraging the bioactive quinoline core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic semiconductors and light-emitting materials.
• Chemical Synthesis: Versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki reactions) due to the reactive bromo and chloro groups.
• Dye & Pigment Industry: Intermediate for synthesizing specialized heterocyclic dyes and colorants.
• Academic & R&D: Essential reagent in medicinal chemistry and organic synthesis research for structure-activity relationship (SAR) studies.

Basic Information

Item	Details
Product Name	4-Amino-3-Bromo-6-Chloroquinoline
CAS No.	1065088-30-3
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	3-Bromo-6-chloro-4-quinolinamine; 4-Quinolinamine, 3-bromo-6-chloro-; 6-Chloro-3-bromo-4-aminoquinoline; 4-Amino-3-bromo-6-chloroquinoline; 3-Bromo-6-chloroquinolin-4-amine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Bromo-6-Chloroquinoline is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.