Description

4-Amino-3-Bromo-8-Fluoroquinoline is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated and aminated structure makes it a valuable scaffold for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its halogenated quinoline core for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecular libraries for drug discovery.
• Material Science: Investigated as a potential monomer or additive for creating specialized polymers and organic electronic materials.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	4-Amino-3-Bromo-8-Fluoroquinoline
CAS No.	1065088-27-8
Molecular Formula	C9H6BrFN2
Molecular Weight	241.06 g/mol
Synonyms	8-Fluoro-4-amino-3-bromoquinoline; 3-Bromo-8-fluoroquinolin-4-amine; 4-Amino-3-bromo-8-fluoro-quinoline; Quinoline, 4-amino-3-bromo-8-fluoro-; 1065088-27-8; 4-Amino-3-bromo-8-fluoroquinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-8-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of this high-value intermediate for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.