Description

4-Amino-3-Bromo-7-Fluoroquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated and aminated quinoline scaffold, which serves as a critical precursor for developing novel pharmacologically active compounds. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in the fields of antibacterial and anticancer research.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel fluoroquinolone antibiotics and other bioactive molecules targeting bacterial DNA gyrase and topoisomerase IV.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities with potential antibacterial, antifungal, or anticancer properties.
• Agrochemical Development: Serves as a building block for creating new crop protection agents, leveraging the biological activity of the quinoline core.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional dyes due to its complexing and chromophoric properties.
• Academic & Industrial R&D: Essential for methodological development in organic synthesis, particularly in cross-coupling and nucleophilic substitution reactions involving halogenated quinolines.

Basic Information

Product Name	4-Amino-3-Bromo-7-Fluoroquinoline
CAS No.	1065088-25-6
Molecular Formula	C9H6BrFN2
Molecular Weight	241.06 g/mol
Synonyms	3-Bromo-7-fluoroquinolin-4-amine; 7-Fluoro-3-bromo-4-aminoquinoline; 4-Amino-7-fluoro-3-bromoquinoline; 4-Quinolinamine, 3-bromo-7-fluoro-; 3-Bromo-7-fluoro-4-quinolinamine; 1065088-25-6 (CAS); 4-Amino-3-bromo-7-fluoro-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-7-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere for prolonged procedures to minimize risk of degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.