Description

4-Amino-3-Bromo-8-Trifluoromethoxyquinoline is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethoxy and bromo substituents, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by fine chemical manufacturers producing specialized intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobials, and other biologically active heterocycles.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, where the trifluoromethoxy group can enhance metabolic stability and lipophilicity.
• Material Science Precursor: Serves as a specialized monomer or ligand in the development of advanced organic materials, such as organic light-emitting diodes (OLEDs) or metal-organic frameworks (MOFs).
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring complex, fluorinated quinoline derivatives.

Basic Information

Product Name	4-Amino-3-Bromo-8-Trifluoromethoxyquinoline
CAS No.	1065088-19-8
Molecular Formula	C11H7BrF3N2O
Molecular Weight	305.09 g/mol
Synonyms	3-Bromo-4-amino-8-(trifluoromethoxy)quinoline; 8-(Trifluoromethoxy)-3-bromoquinolin-4-amine; 4-Amino-3-bromo-8-(trifluoromethoxy)quinoline; 4-Amino-3-bromo-8-trifluoromethoxyquinoline; 3-Bromo-8-trifluoromethoxyquinolin-4-ylamine; Quinoline, 4-amino-3-bromo-8-(trifluoromethoxy)-; 1065088-19-8
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-8-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.