Description

4-Amino-3-Bromo-7-Trifluoromethoxyquinoline is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethoxy and bromo substituents, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in medicinal chemistry for creating potential drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for the synthesis of functional organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	4-Amino-3-Bromo-7-Trifluoromethoxyquinoline
CAS No.	1065088-17-6
Molecular Formula	C₁₁H₇BrF₃N₂O
Molecular Weight	321.09 g/mol
Synonyms	3-Bromo-4-amino-7-(trifluoromethoxy)quinoline; 7-(Trifluoromethoxy)-3-bromoquinolin-4-amine; 4-Amino-3-bromo-7-(trifluoromethoxy)quinoline; 3-Bromo-7-trifluoromethoxy-quinolin-4-ylamine; 4-Amino-3-bromo-7-trifluoromethoxyquinoline; 1065088-17-6; Quinoline, 4-amino-3-bromo-7-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Bromo-7-Trifluoromethoxyquinoline is produced under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.