Description

3-Bromo-6,8-Difluoro-4-Hydroxyquinoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its unique halogenated and fluorinated quinoline structure, which serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antimicrobial, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLEDs and sensors, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags and molecular probes for diagnostic and research applications.
• Catalyst & Ligand Development: Utilized to create novel chelating ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific halogenated quinoline motifs.

Basic Information

Product Name	3-Bromo-6,8-Difluoro-4-Hydroxyquinoline
CAS No.	1065087-96-8
Molecular Formula	C9H4BrF2NO
Molecular Weight	260.04 g/mol
Synonyms	4-Hydroxy-3-bromo-6,8-difluoroquinoline; 6,8-Difluoro-3-bromo-4-quinolinol; 3-Bromo-6,8-difluoro-4-quinolinol; 3-Bromo-6,8-difluoroquinolin-4-ol; Quinoline, 3-bromo-6,8-difluoro-4-hydroxy-; 1065087-96-8; 3-Br-6,8-F2-4-OH-Quinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-6,8-Difluoro-4-Hydroxyquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.