Description

trans-Methyl 4-Methylpyrrolidine-3-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate and chiral building block of significant synthetic utility. Its value lies in its well-defined stereochemistry and functional groups, which are critical for constructing complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on synthesizing novel active ingredients for drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides and herbicides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial R&D for methodological studies and the construction of complex nitrogen-containing heterocycles.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty fine chemicals where precise stereocontrol is necessary.

Basic Information

Product Name	trans-Methyl 4-Methylpyrrolidine-3-Carboxylate Hydrochloride
CAS No.	1065065-28-2
Molecular Formula	C8H16ClNO2
Molecular Weight	193.67 g/mol
Synonyms	trans-Methyl 4-methylpyrrolidine-3-carboxylate HCl; (3R,4S)-Methyl 4-methylpyrrolidine-3-carboxylate hydrochloride; (3S,4R)-Methyl 4-methylpyrrolidine-3-carboxylate hydrochloride; Methyl (3R,4S)-4-methylpyrrolidine-3-carboxylate hydrochloride; 4-Methylpyrrolidine-3-carboxylic acid methyl ester hydrochloride (trans-); 3-Pyrrolidinecarboxylic acid, 4-methyl-, methyl ester, hydrochloride, (3R,4S)-rel-; trans-4-Methyl-3-pyrrolidinecarboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our trans-Methyl 4-Methylpyrrolidine-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.