Description

(3-Cyclopropyl-4-Fluorophenyl)Methanamine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, combining a cyclopropyl group and a fluorine atom on a benzylamine scaffold, which is valuable for modulating the physicochemical and pharmacological properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorinated cyclopropyl moiety can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, leveraging the amine functionality for metal coordination or activation.
• Material Science: Employed in the synthesis of specialty polymers, dyes, or liquid crystals, where its aromatic and amine groups can be incorporated into larger conjugated systems.
• Chemical Biology Probe: Utilized as a tagged amine for bioconjugation or as a core structure in the design of molecular probes for studying biological systems.

Basic Information

Product Name	(3-Cyclopropyl-4-Fluorophenyl)Methanamine
CAS No.	1063733-90-3
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	1-(3-Cyclopropyl-4-fluorophenyl)methanamine; (3-Cyclopropyl-4-fluorobenzyl)amine; 3-Cyclopropyl-4-fluorobenzylamine; 4-Fluoro-3-cyclopropylbenzenemethanamine; α-Amino-3-cyclopropyl-4-fluorotoluene; Benzenemethanamine, 3-cyclopropyl-4-fluoro-; 1063733-90-3
EINECS	Contact for details

Quality Control

Our (3-Cyclopropyl-4-Fluorophenyl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.