Description

2-Pyridinecarboxylic Acid, 5-(Chlorosulfonyl)-, Methyl Ester is a high-purity, specialized chemical intermediate featuring a reactive chlorosulfonyl group on a pyridine scaffold. This compound matters for its role as a critical building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its reactive site for creating new compound libraries.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of functional polymers and advanced organic electronic materials due to its conjugated pyridine system.
• Chemical Biology Probes: Utilized as a starting material for synthesizing molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable intermediate for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Pyridinecarboxylic Acid, 5-(Chlorosulfonyl)-, Methyl Ester
CAS No.	1063733-25-4
Molecular Formula	C8H8ClNO4S
Molecular Weight	249.67 g/mol
Synonyms	Methyl 5-(chlorosulfonyl)picolinate; 5-(Chlorosulfonyl)picolinic Acid Methyl Ester; Methyl 5-Chlorosulfonylpyridine-2-carboxylate; 2-Pyridinecarboxylic Acid, 5-(Chlorosulfonyl)-, Methyl Ester; Picolinic Acid, 5-(Chlorosulfonyl)-, Methyl Ester; 5-Chlorosulfonyl-2-pyridinecarboxylic Acid Methyl Ester; Methyl 5-Chlorosulfonyl-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylic Acid, 5-(Chlorosulfonyl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive chlorosulfonyl group, it is recommended to store under an inert atmosphere for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.