Description

3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, Phenylmethyl Ester is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic diamine structure. This compound is critical for medicinal chemistry research and development, serving as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on central nervous system (CNS) therapeutics, protease inhibitors, and other complex small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a privileged scaffold in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its constrained spirocyclic geometry.
• Protease Inhibitor Development: The diamine moiety makes it a valuable building block for creating inhibitors of various protease enzymes.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects under cGMP guidelines.

Basic Information

Product Name	3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, Phenylmethyl Ester
CAS No.	1061755-67-6
Molecular Formula	C17H24N2O2
Molecular Weight	288.39 g/mol
Synonyms	Benzyl 3,9-diazaspiro[5.5]undecane-3-carboxylate; 3,9-Diazaspiro[5.5]undecane-3-carboxylic acid benzyl ester; 3-Carboxy-3,9-diazaspiro[5.5]undecane benzyl ester; Spiro[5.5]diazecine-3-carboxylic acid, phenylmethyl ester; 3-Benzyloxycarbonyl-3,9-diazaspiro[5.5]undecane; 3,9-Diazaspiro[5.5]undecane-3-carboxylic acid, benzyl ester; 1061755-67-6
EINECS	Contact for details

Quality Control

Our 3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, Phenylmethyl Ester is manufactured under strict quality management systems. We offer material suitable for research and development use, with purity levels typically exceeding 97% (by HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. For advanced applications, we provide material produced under cGMP-like controls and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.