Description

3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 8-Oxo-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Used in the development and scale-up of new Active Pharmaceutical Ingredients (APIs), especially those containing complex spirocyclic or diazaspiroundecane motifs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis methodology development and novel heterocycle exploration.

Basic Information

Product Name	3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 8-Oxo-, Methyl Ester
CAS No.	1061731-96-1
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	Methyl 8-oxo-3,9-diazaspiro[5.5]undecane-3-carboxylate; 3,9-Diazaspiro[5.5]undecane-3-carboxylic acid, 8-oxo-, methyl ester; 8-Oxo-3,9-diazaspiro[5.5]undecane-3-carboxylic acid methyl ester; Spirocyclic diaza compound 1061731-96-1; Methyl 8-oxo-3,9-diazaspiro[5.5]undecane-3-carboxylate (IUPAC); CAS 1061731-96-1
EINECS	Contact for details

Quality Control

Our 3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 8-Oxo-, Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support development work through to pre-clinical and clinical stage manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.