Description

1-(2-Chloropyridin-4-Yl)Cyclopropanecarboxylic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its core value lies in the strategic combination of a chloropyridine moiety and a strained cyclopropane ring, enabling the synthesis of complex molecules with targeted biological activity. This compound is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including potential kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents, leveraging its unique heterocyclic structure for bioactivity.
• Chemical Biology Probe Development: Serves as a versatile scaffold for constructing molecular probes to study biological pathways and protein functions.
• Material Science Research: Acts as a precursor for specialty polymers or ligands in catalytic systems, exploring its rigid, three-dimensional geometry.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring sophisticated chemical transformations.

Basic Information

Product Name	1-(2-Chloropyridin-4-Yl)Cyclopropanecarboxylic Acid
CAS No.	1060811-78-0
Molecular Formula	C9H8ClNO2
Molecular Weight	197.62 g/mol
Synonyms	1-(2-Chloro-4-pyridinyl)cyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 1-(2-chloro-4-pyridinyl)-; 1-(2-Chloropyridin-4-yl)cyclopropane-1-carboxylic acid; 1-(2-Chloro-4-pyridyl)cyclopropanecarboxylic acid; 4-(1-Carboxycyclopropyl)-2-chloropyridine; 2-Chloro-4-(1-carboxycyclopropyl)pyridine; 1060811-78-0
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloropyridin-4-Yl)Cyclopropanecarboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.