Description

6-Amino-2-Trifluoromethyl-Nicotinic Acid is a high-purity, multi-functional chemical building block of significant commercial and research interest. Its core value lies in its unique molecular structure, which combines a nicotinic acid scaffold with amino and trifluoromethyl substituents, making it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought after by pharmaceutical and agrochemical R&D sectors for the development of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors or light-emitting components, due to its electron-deficient aromatic system.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.

Basic Information

Item	Detail
Product Name	6-Amino-2-Trifluoromethyl-Nicotinic Acid
CAS No.	1060810-75-4
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	2-Trifluoromethyl-6-aminonicotinic acid; 6-Amino-2-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Carboxy-2-(trifluoromethyl)-6-aminopyridine; 6-Amino-2-trifluoromethyl-3-pyridinecarboxylic acid; 2-(Trifluoromethyl)-6-aminopyridine-3-carboxylic acid; 6-Amino-α,α,α-trifluoro-2-picolinic acid; 6-Amino-2-trifluoromethylnicotinic acid
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Trifluoromethyl-Nicotinic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.