Description

2-Bromo-4-Fluoronicotinic Acid is a high-purity halogenated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which enables the precise introduction of bromine and fluorine substituents into complex heterocyclic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Employed as a precursor for synthesizing functionalized ligands and complex organic molecules for electronic materials.
• Chemical Biology: Serves as a versatile probe or building block for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing tailored compounds for client R&D.

Basic Information

Product Name	2-Bromo-4-Fluoronicotinic Acid
CAS No.	1060809-35-9
Molecular Formula	C6H3BrFNO2
Molecular Weight	219.99 g/mol
Synonyms	4-Fluoro-2-bromonicotinic Acid; 2-Bromo-4-fluoropyridine-3-carboxylic Acid; 3-Carboxy-2-bromo-4-fluoropyridine; 1060809-35-9; Nicotinic acid, 2-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoronicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.