Description

6-Chloro-4-Fluoro Nicotinic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound matters because its unique halogenated pyridine structure serves as a critical precursor for creating advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its halogenated nicotinic acid scaffold.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.
• Academic and R&D Laboratories: Used in fundamental research to explore new chemical reactions and biological activities.

Basic Information

Product Name	6-Chloro-4-Fluoro Nicotinic Acid
CAS No.	1060809-30-4
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.55 g/mol
Synonyms	4-Fluoro-6-chloronicotinic acid; 6-Chloro-4-fluoropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-chloro-4-fluoro-; Nicotinic acid, 6-chloro-4-fluoro-; 6-Chloro-4-fluoro-3-pyridinecarboxylic acid; 1060809-30-4; 6-Chloro-4-fluoronicotinic acid
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Fluoro Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.