Description

4-Bromo-2-Chloropyridine-3-Carboxylic Acid is a high-purity halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic and Industrial R&D: Used in exploratory chemistry for developing new synthetic methodologies and discovering novel chemical entities.

Basic Information

Product Name	4-Bromo-2-Chloropyridine-3-Carboxylic Acid
CAS No.	1060805-68-6
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	3-Carboxy-4-bromo-2-chloropyridine; 2-Chloro-4-bromonicotinic Acid; 4-Bromo-2-chloropyridine-3-carboxylic acid; 4-Bromo-2-chloro-3-pyridinecarboxylic acid; 2-Chloro-4-bromo-3-pyridinecarboxylic acid; Nicotinic acid, 4-bromo-2-chloro-; 1060805-68-6
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-Chloropyridine-3-Carboxylic Acid adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Anhydrous basis)
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.