Description

1-(3-Bromophenyl)Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine carboxylic acid core and bromophenyl substituent. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Chemical Synthesis Building Block: Provides a versatile scaffold for constructing more complex heterocyclic compounds and fine chemicals.
• Biochemical Tool Compound: Potential use in biochemical assays and as a ligand or inhibitor in pharmacological studies.
• Academic & Industrial R&D: Employed in research laboratories for developing new synthetic methodologies and exploring chemical space.

Basic Information

Product Name	1-(3-Bromophenyl)Piperidine-4-Carboxylic Acid
CAS No.	1059536-36-5
Molecular Formula	C12H14BrNO2
Molecular Weight	284.15 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(3-bromophenyl)-; 1-(3-Bromophenyl)-4-piperidinecarboxylic acid; 1-(3-Bromophenyl)piperidine-4-carboxylic acid; 3-Bromo-1-piperidin-1-ylbenzene-4-carboxylic acid; 1-(m-Bromophenyl)piperidine-4-carboxylic acid; 1059536-36-5; 1-(3-Bromophenyl)isonipecotic acid
EINECS	Contact for details

Quality Control

Our production of 1-(3-Bromophenyl)Piperidine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP-compliant applications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.