Description

Chloro[(1,3-Dimesitylimidazol-2-ylidene)(N,N-dimethylbenzylamine)palladium(II)] is a highly active and versatile N-heterocyclic carbene (NHC) palladium complex, prized for its exceptional stability and catalytic efficiency. This compound is a cornerstone catalyst for demanding cross-coupling reactions, enabling the synthesis of complex organic molecules with high selectivity and yield. It is an essential tool for researchers and process chemists in pharmaceutical development, advanced material science, and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling: Catalyzes the coupling of aryl/vinyl boronic acids with aryl/vinyl halides for biaryl synthesis.
• Buchwald-Hartwig Amination: Enables the formation of C-N bonds for the synthesis of aryl amines and amides.
• Heck (Mizoroki-Heck) Reaction: Facilitates the coupling of alkenes with aryl/vinyl halides.
• Negishi Coupling: Catalyzes the cross-coupling of organozinc reagents with organic halides.
• Pharmaceutical Intermediate Synthesis: Key catalyst for constructing complex scaffolds in active pharmaceutical ingredient (API) development.
• Material Science Research: Used in the synthesis of conjugated polymers and organic electronic materials.
• Methodology Development: A preferred catalyst for developing new synthetic methodologies in academic and industrial R&D.

Basic Information

Item	Details
Product Name	Chloro[(1,3-Dimesitylimidazol-2-ylidene)(N,N-dimethylbenzylamine)palladium(II)]
CAS No.	1058661-78-1
Molecular Formula	C29H34ClN3Pd
Molecular Weight	558.45 g/mol
Synonyms	Palladium NHC Complex; PEPPSI-IPentTM Cl; (1,3-Bis(2,4,6-trimethylphenyl)imidazol-2-ylidene)(N,N-dimethylbenzylamine)palladium(II) chloride; Pd-PEPPSI-IPent; [Pd(IPent)(BnNMe2)Cl]; NHC-Pd Catalyst; Palladium(II) chloro[1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene](N,N-dimethylbenzylamine)
EINECS	Contact for details

Quality Control

Every batch of our Chloro[(1,3-Dimesitylimidazol-2-ylidene)(N,N-dimethylbenzylamine)palladium(II)] is synthesized and handled under inert atmosphere to ensure maximum catalytic activity and purity. We employ rigorous analytical techniques including NMR, HPLC, and elemental analysis to verify identity and purity, ensuring compliance with stringent R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is moisture-sensitive (hygroscopic) and easily oxidized; prolonged exposure to air or moisture will degrade catalytic performance.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Palladium (Pd) Content	~19.0%
Solubility	Soluble in common organic solvents (DCM, THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.