Description

4-Ethynyl-3-Methoxy-Phenol is a high-purity, multi-functional phenolic building block featuring both an ethynyl and a methoxy substituent. This unique molecular structure makes it a valuable intermediate for synthesizing complex organic molecules, particularly in advanced material science and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic electronic materials.
• Chemical Research: A versatile reagent in organic synthesis, particularly for Sonogashira coupling and other palladium-catalyzed reactions to create complex molecular architectures.
• Liquid Crystal & OLED Materials: Used in the synthesis of organic semiconductors and liquid crystal compounds for display technologies.

Basic Information

Product Name	4-Ethynyl-3-Methoxy-Phenol
CAS No.	1057670-07-1
Molecular Formula	C9H8O2
Molecular Weight	148.16 g/mol
Synonyms	3-Methoxy-4-ethynylphenol; 4-Ethynylguaiacol; 4-(Ethynyl)-3-methoxyphenol; 2-Methoxy-4-ethynylphenol; Guaiacol, 4-ethynyl-; Phenol, 4-ethynyl-3-methoxy-; 1057670-07-1
EINECS	Contact for details

Quality Control

Our 4-Ethynyl-3-Methoxy-Phenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide regulatory documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.