Description

5-Bromo-3-Chloro-1-Methyl-1H-Indole-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its precise molecular architecture, which serves as a critical scaffold for constructing complex pharmacologically active molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly those focused on developing new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic & R&D: Fundamental research tool in universities and corporate R&D labs for exploring new chemical reactions and heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-3-Chloro-1-Methyl-1H-Indole-2-Carboxylic Acid
CAS No.	1057404-45-1
Molecular Formula	C10H7BrClNO2
Molecular Weight	288.52 g/mol
Synonyms	5-Bromo-3-chloro-1-methylindole-2-carboxylic acid; 1-Methyl-5-bromo-3-chloroindole-2-carboxylic acid; 2-Carboxy-5-bromo-3-chloro-1-methylindole; 5-Bromo-3-chloro-1-methyl-1H-indole-2-carboxylic acid; 1057404-45-1; 5-Br-3-Cl-1-Me-indole-2-COOH
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Chloro-1-Methyl-1H-Indole-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.