Description

(4-Iodo-Pyridin-2-Yl)-Hydrazine is a specialized heterocyclic building block featuring a reactive hydrazine group adjacent to an iodine substituent on a pyridine ring. This unique molecular architecture makes it a critical intermediate for the synthesis of complex pharmacophores and advanced materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel nitrogen-containing compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with specific modes of action.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Heterocyclic Chemistry: A versatile building block for constructing fused pyridine, pyridazine, and other N-heterocyclic systems via cyclization reactions.
• Cross-Coupling Reactions: The iodine atom facilitates further functionalization via palladium-catalyzed cross-coupling (e.g., Suzuki, Sonogashira) to introduce diverse aryl or alkynyl groups.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes.

Basic Information

Product Name	(4-Iodo-Pyridin-2-Yl)-Hydrazine
CAS No.	1057393-44-8
Molecular Formula	C5H6IN3
Molecular Weight	235.03 g/mol
Synonyms	2-Hydrazinyl-4-iodopyridine; 4-Iodo-2-hydrazinopyridine; (4-Iodopyridin-2-yl)hydrazine; 4-Iodopyridine-2-ylhydrazine; 2-Pyridinylhydrazine, 4-iodo-; (4-Iodo-2-pyridinyl)hydrazine
EINECS	Contact for details

Quality Control

Our (4-Iodo-Pyridin-2-Yl)-Hydrazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.