Description

3-Azaspiro[5.5]Undecane-3-Carboxylic Acid, 9-Oxo-,Phenylmethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and ester functional groups. This compound is critical for enabling sophisticated synthetic routes in modern medicinal chemistry, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those with spirocyclic architectures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of inhibitors targeting specific enzymatic pathways.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	3-Azaspiro[5.5]Undecane-3-Carboxylic Acid, 9-Oxo-,Phenylmethyl Ester
CAS No.	1056629-20-9
Molecular Formula	C17H21NO3
Molecular Weight	287.35 g/mol
Synonyms	Benzyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate; 3-Carboxy-9-oxo-3-azaspiro[5.5]undecane Phenylmethyl Ester; 9-Oxo-3-azaspiro[5.5]undecane-3-carboxylic Acid Benzyl Ester; Benzyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate; 3-Azaspiro[5.5]undecane-3-carboxylic acid, 9-oxo-, phenylmethyl ester; 1056629-20-9; Spirocyclic Ester Intermediate
EINECS	Contact for details

Quality Control

Our production of 3-Azaspiro[5.5]Undecane-3-Carboxylic Acid, 9-Oxo-,Phenylmethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.