Description

(1R,2R)-(-)-1,2-Bis(4-Hydroxyphenyl)Ethylenediaminedihydrochloride is a high-purity, chiral diamine derivative with significant utility in advanced chemical synthesis. This compound matters as a sophisticated chiral building block and ligand, enabling the production of enantiomerically pure products critical for modern pharmaceuticals and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in asymmetric catalysis and the development of active pharmaceutical ingredients (APIs).

Application

• As a chiral ligand or catalyst in asymmetric synthesis reactions, including hydrogenation and C-C bond formation.
• As a key intermediate in pharmaceutical research for the development of novel therapeutic agents.
• In the synthesis of complex macrocyclic compounds and chelating agents for metal coordination chemistry.
• For the preparation of chiral stationary phases used in high-performance liquid chromatography (HPLC) for enantiomer separation.
• As a building block in agrochemical research for creating enantiopure pesticides or herbicides.
• In academic and industrial R&D for studying stereoselective reaction mechanisms and developing new catalytic systems.

Basic Information

Item	Details
Product Name	(1R,2R)-(-)-1,2-Bis(4-Hydroxyphenyl)Ethylenediaminedihydrochloride
CAS No.	1055301-14-8
Molecular Formula	C14H18N2O2 · 2HCl
Molecular Weight	323.22 g/mol (Free base: 258.31 g/mol)
Synonyms	(1R,2R)-1,2-Bis(4-hydroxyphenyl)ethylenediamine dihydrochloride; (R,R)-H4pen dihydrochloride; (1R,2R)-(-)-1,2-Di(4-hydroxyphenyl)ethylenediamine dihydrochloride; (R,R)-1,2-Bis(4-hydroxyphenyl)-1,2-ethanediamine dihydrochloride; (R,R)-Tetrahydroxydiphenylethylenediamine dihydrochloride; (R,R)-THPED · 2HCl; (1R,2R)-H8pen · 2HCl
EINECS	Contact for details

Quality Control

Our (1R,2R)-(-)-1,2-Bis(4-Hydroxyphenyl)Ethylenediaminedihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.