Description

1-(4-Bromobenzyl)Azetidin-3-Ol is a high-purity azetidine derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its unique heterocyclic structure, which serves as a critical scaffold for developing novel pharmaceutical compounds and fine chemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized azetidine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a building block for developing new generation herbicides, fungicides, and plant growth regulators with improved efficacy.
• Ligand & Catalyst Development: Serves as a functionalized backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate for synthesizing specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and the development of molecular probes.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and scale-up projects.

Basic Information

Product Name	1-(4-Bromobenzyl)Azetidin-3-Ol
CAS No.	1054483-33-8
Molecular Formula	C10H12BrNO
Molecular Weight	242.11 g/mol
Synonyms	3-Hydroxy-1-[(4-bromophenyl)methyl]azetidine; 1-[(4-Bromophenyl)methyl]azetidin-3-ol; 1-(4-Bromobenzyl)-3-hydroxyazetidine; Azetidin-3-ol, 1-[(4-bromophenyl)methyl]-; 1054483-33-8
EINECS	Contact for details

Quality Control

Our 1-(4-Bromobenzyl)Azetidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.